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This phase is primarily for acclimation, helping your body get used to the medication and reducing the risk of gastrointestinal side effects like nausea or vomiting

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AstraZeneca developed the orally optimized GLP-1 analogue, MEDI7219, through amino-acid substitutions and bis-lipidation, followed by PE screening to identify the combination of sodium chenodeoxycholate (NaCDC) and propyl gallate (PG) as potential excipients (Pechenov et al., 2021)

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