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By slowing stomach emptying and enhancing satiety signals, these shots help patients feel fuller faster and longer, leading to reduced calorie intake without the constant frustration of restrictive dieting

Peter Lurie, a former FDA associate commissioner and executive director of the Center for Science in the Public Interest

However, for patients with pre-existing gastrointestinal conditions such as gastroparesis (paralyzed stomach), severe gastroesophageal reflux disease (GERD), or inflammatory bowel disease (IBD), this mechanism can exacerbate symptoms

In CON, the non-mitochondrial respiration rate ( Figure 9A ) remained at the baseline level throughout the experiment