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This result is consistent with the presence of four ionizable amino acids in EXE (lysine, 2 histidine, and arginine) under acidic conditions, enabling complete charge neutralization in the presence of the four anionic charges provided by the single-charged counter parts, as previously reported by Ristroph and Prudhomme (2019)

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Vaughan, MD , the director of the Potocsnak Longevity Institute at Northwestern Universitys Feinberg School of Medicine in Chicago