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Mechanistically, flavonoids act by concurrently modulating multiple interconnected signaling pathways, reshaping the immune network in a mild yet sustained manner rather than strongly suppressing a single pathway

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Tachykinins are involved in a cough reflex and in the inflammatory response in the lungs, as they were shown to be important mediators of the neurogenic inflammation in asthma, allergic rhinitis and chronic bronchitis [119]