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The SURMOUNT-5 trial (clinicaltrials.gov identifier NCT05822830) was conducted in accordance with the International Conference on Harmonisation Guidelines for Good Clinical Practice and the Declaration of Helsinki

In the present study, eotaxin-1 and IL-1 concentrations were significantly elevated in the HFD and OVA + HFD groups

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The typical adult dose is 250500 mg twice daily, though it should always be taken at the lowest effective dose for the shortest duration necessary, following prescriber guidance