When safety of the study participants and technological developments allow, so called biomarkers can be used to collect PD data to understand if the drug reaches the target, binds to the target and exerts its expected pharmacological activity within the dose range tested
Biochemistry 41:70087020 Tripathi A, Indoliya Y, Tiwari M, Tiwari P, Srivastava D, Verma PK, Verma S, Gautam N, Chakrabarty D (2014) Transformed yeast ( Schizosaccharomyces pombe ) overexpressing rice tau class glutathione S-transferase (OsGSTU30 and OsGSTU41) shows enhanced resistance to hexavalent chromium
Glutathione vs Vitamin C for Whitening Which Wins for Pakistani Skin
(2010) Selenium, but not lycopene or vitamin E, decreases growth of transplantable dunning R3327-H rat prostate tumors