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Cancer 109(6):1152-1156, 2007

Costs vary widely, and oral forms are not always less expensive than injectables

Months 3, 5, 7: Technical progress reports detailing technical progress made, tasks accomplished, major risks/mitigations, a technical plan for the remainder of Phase II (while this will normally report progress against the plan detailed in the proposal or presented at the Kickoff briefing, it is understood that scientific discoveries, competition, and regulatory changes may all have impacts on the planned work and DARPA must be made aware of any revisions that result), planned activities, trip summaries, and any potential issues or problem areas that require the attention of the DARPA PM

Yes, berberine can lower blood glucose and may potentiate the effects of metformin, sulphonylureas, or insulin, increasing hypoglycaemia risk