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We envisioned that the lysine residue could be formed by reductive amination of allysine, which in turn could be synthesized by a hydroformylation process (HFP) of an allylglycine residue directly within peptides

Approximately equal numbers of patients were randomized to receive initial therapy with 100 mg of JANUVIA in combination with 30 mg of pioglitazone once daily or 30 mg of pioglitazone once daily as monotherapy

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