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Participants were given 3 g of L-carnitine per day for 3 months and blood samples were taken each morning after fasting overnight to assess their levels of fasting glucose (blood sugar), insulin, triglycerides, high density lipoprotein (HDL), low density lipoprotein (LDL), free testosterone, dehydroepiandrosterone (DHEA), and their insulin resistance index (HOMA-IR)

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In skeletal muscle fibers, excitationcontraction coupling leads to the release of calcium from the sarcoplasmic reticulum and increases intracellular calcium concentrations (Stamler and Meissner, 2001)