This was evident when comparing exenatide and semaglutide chromatographic profiles: exenatide, a non-lipidated peptide with several acidic residues, was strongly affected by NSA (likely due to ionic and dipole-ionic interactions with metal surfaces), leading to decreased efficiency
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J Plast Reconstr Aesthet Surg 60:114118 Virmani A, Koverech A, Ali SF, Binienda ZK (2011) Acetyl-l-carnitine modulates TP53 and IL10 gene expression induced by 3-NPA evoked toxicity in PC12 cells