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Notably, the potential of hydrogen interventions to alleviate non-motor symptoms, such as constipation and sleep disorders, may address the limitations of existing therapies (Pluta et al., 2022)

How compartment-specific GSH metabolism modulates GPX4 activity during ferroptotic stress remains an important unresolved question

The outcome suggested that a transient and limited increase in gut permeability compared with the unregulated breach of the gut barrier function due to the TJ deregulation and epithelial cell apoptosis can rather lead to a dominant regulatory immune response to gut microbiota antigens and to a net anti-inflammatory effect

160 Exposing sperm from men with infertility to a melatonin-enriched environment was found in one study to reduce DNA fragmentation and increase viability