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For a scientific overview of the microbiome, the difference between GLP-1 agonist drugs and microbial approaches to regulating GLP-1, and the role GLP-1 plays in helping to maintain a healthy weight, please refer to the white paper: Harnessing GLP-1 in the digestive tract for better metabolic health
This means they have been evaluated for safety and efficacy in clinical trials
In a combined multiple ascending dose and Phase IIa study in people with type 2 diabetes over 41 days, daily doses of cotadutide up to 200 g improved fasting and postprandial glucose levels and reduced body weight compared with placebo [79]
I wouldn't prescribe it under any circumstances
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