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Most side effects are mild and temporary, such as flushing, mild nausea, or soreness at the injection site

Alternative Weight Management Options if Saxenda Isn't Working If Saxenda fails to produce adequate appetite suppression or weight loss after 12 weeks at the maintenance dose (defined by NICE as less than 5% body weight loss), your clinician should review your treatment plan and consider alternative approaches

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The glucagon receptor component is thought largely on the basis of preclinical data to increase energy expenditure and promote fat breakdown (lipolysis), which may contribute to the substantial weight loss observed in early trials