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Higher doses or extended treatment plans typically increase the overall cost

G.GeertsM.van KleefM.MerkiesI

Additionally, some patients remove the pen too quickly after injection, before the full dose is delivered, resulting in medication wastage and underdosing

During the process of apoptosis, release of excessive quantity of intact nucleosomes has been suggested to be a source of nuclear antigens that drive an immune response, inducing anti-DNA and anti-histone antibody production [93,94]