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.,SantivarangknaC,KulozikUFoerstPInactivation mechanisms of lactic acid starter cultures preserved by drying processes.2008;105(1):113 81

If a higher dose is required to achieve proper glycemic control, the dose may then be increased to 1.0 mg once-weekly, assuming the tolerance is adequate

Preservatives in the medication help keep it sterile for a period, but those preservatives also break down over time

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