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This marker may reflect shifts in fat utilization, so clinicians may want to monitor it

In the first nine months of 2025, Mounjaro and Zepbound generated combined sales of $24.8 billion for the company (accounting for 54% of Eli Lillys revenue)

Moreover, it has recently been reported that metformin inhibits the apical sodium-dependent bile acid transporter and thus may increase the concentration of bile acids in the intestine [12], which could stimulate GLP-1 secretion from L cells via the G-protein-coupled receptor TGR5 [13]

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