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Epitalon has been studied for its potential role in telomerase activation and pineal gland function

The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy

Comorbidities included hypertensive diseases (I10-I16), Type 2 diabetes mellitus (E11), chronic lower respiratory diseases (J40-J47), neoplasms (C00-D49), psychoactive substance use (F10-F19), ischemic heart diseases (I20-I25), chronic kidney disease (N18), and cerebrovascular diseases (I60-I69)

For assessing membrane permeability, the team employed the parallel artificial membrane permeability assay (PAMPA) and utilized an MDCK cell clone that expressed low levels of P-glycoprotein to minimize transporter-mediated efflux effects