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Furthermore, exogenous GLP-1 can protect the intestine from oxidative damage by inhibiting neutrophil infiltration, and can reduce inflammatory mediators that induce LPO production, regulate intestinal homeostasis through local effects and restore intestinal integrity, thereby reducing bacterial translocation caused by intestinal barrier dysfunction (128)

This article examines which peptides are FDA-approved , which remain research-only , and how clinicians can ethically navigate this rapidly evolving field