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Radiesse lasts 1 year or longer

The resulting tiredness persists despite adequate rest and does not respond to early bedtimes or caffeine

Bioinformatics 21 , 32863293 (2005)

PQQ exposed mice showed a significant decline in neuroinflammations, and expression levels of NO, PGE2, pro-inflammatory factors (iNOS, COX-2, TNF-a, IL-1b, IL-6, MCP-1 and MIP-1a) in LPS treated primary microglia cells was declined to a notable extent (Yang et al., 2014a)