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Improper storage causes irreversible peptide degradation: temperatures above 30C denature protein structure within 2 hours, freezing reconstituted peptides creates ice crystals that aggregate peptide molecules, and storing lyophilised vials in humid environments introduces moisture that hydrolyzes peptide bonds even before reconstitution

Intracellular GSH balance is maintained by de novo synthesis, regeneration from GSSG, and extracellular GSH uptake

The dimeric form of GPI is a prerequisite for catalytic activity because the active site of the enzyme is composed of polypeptide chains from both subunits.50,145 The gene encoding GPI (GPI) is located on chromosome 19q13.1 and consists of 18 exons, spanning at least 50 kb, with a cDNA 1.9 kb in length

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