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That long half-life is also why titration steps are held for about four weeks rather than a few days: it takes several weekly doses for blood levels to plateau at each new rung of the ladder before the next increase makes sense

He took the concept one step further: Instead of locating cytoprotection primarily in the stomach, or in the GI tract, he theorized that the peptide could preserve blood vessels and thus protect tissue across every organ of the body

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A 2009 rat study tested ipamorelin alone (300 mcg/kg), CJC-1295 alone (100 mcg/kg), and the combination