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Retatrutide combines agonism of GIP, GLP-1, and Glucagon receptors in a single molecule, a physiological strategy that researchers believe can unlock even greater metabolic potential

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Despite the importance of the new standard, advocates criticized the commission for setting lower thresholds for ethylene oxides non-cancer health effects, aligning with proposals supported by business groups

These findings are summarised in Figure 1 below and highlight the broad therapeutic potential of GLP-1s across multiple disease areas