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No evidence of increase in calcitonin concentrations or development of C-cell malignancy in response to liraglutide for up to 5 years in the LEADER Trial

Laser Doppler Flowmetry Gingival blood flow (GBF) was measured by laser doppler flowmetry (LDF, Oxford Optronix Ltd, Oxford, UK) working at 780 nm

However, the course of treatment should be at least 6 months to obtain good results, which may have side effects, including skin atrophy, telangiectasia (spider vein, dilation of blood vessels), and acneiform eruptions (in this case, it is advisable to switch to topical immunomodulators)

Taking it first thing in the morning, at least 20 to 30 minutes before breakfast, is a common and effective routine