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The metabolic syndrome is defined as a clustering of atherosclerotic cardiovascular disease risk factors that include visceral adiposity (obesity), insulin resistance, low levels of HDLs and a systemic proinflammatory state

Further, to what we already showed [i.e., testosterone increased IGF-1 gene expression during RET (Gharahdaghi et al., 2019)], both testosterone and estrogen blunted IGF-I feedback-dependent inhibition of GH secretion (Veldhuis et al., 2004, 2005)

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