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observed that in T2DM patients (mean age: 64.9 years) treated with subcutaneous semaglutide, reductions in the SMI were smaller than those in the fat mass index (FMI) [56], and the findings suggest a preservation of muscle strength and muscle quality

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The featured molecule, 13 , proved to be an XO inhibitor, and with an IC 50 value of 4.261 M, the compound was more potent than allopurinol, the drug used as a positive control with an IC 50 value of 4.678 M (Figure 7)