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Early placebo-controlled randomized controlled trials (RCTs) of GLP-1RAs conducted in patients with obesity and type 2 diabetes suggested beneficial effects on the liver, including improvements in liver biochemistries suggesting reduction in inflammation

This article was medically reviewed by Renae Thomas, MD, MPH

PRECLINICAL STUDY: Ghrelin administration into tegmental areas stimulates locomotor activity and increases extracellular concentration of dopamine in the nucleus accumbens