These mechanisms occur within hours after GCs administration and may lead to hyperglycemia, even in individuals without a prior history of glucose abnormalities ( Figure 1 The clinical impact of hyperglycemia during GCs therapy has been well established, with multiple studies reporting increased morbidity and mortality, including higher rates of infection, cardiovascular events and prolonged hospitalisations ( Although glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are not currently recommended in SID by major guidelines, their mechanism of action makes them promising candidates to counteract the metabolic impacts of steroids
Egg muffin cups These are one of the easiest freezer breakfasts for GLP-1 mornings because they stay small, soft, and ready to grab
Bloomer RJ, Tschume LC, Smith WA
Pharmaceuticals (Basel) 17(12):1655 Picoli CC, Tsibulnikov S, Ho M, Demambro V, Feng T, Eltahir M, Le PT, Chlebek C, Rosen CJ, Ryzhov S, Li Z (2025) Vertical sleeve gastrectomy and semaglutide have distinct effects on skeletal health and heart function in obese male mice