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In a RDP clinical trial with 200 peri-menopausal women, a significant decrease of LDL cholesterol by 9.9% and a significant increase of HDL cholesterol by 4.6% were observed after six months of Pycnogenol (200 mg) supplementation ( supplementation by 3.9 and 3.5%, respectively, while after placebo systolic and diastolic blood pressures were decreased by 1.7 and 1%, respectively

The compound's ability to reverse age-related deficits in fitness, fur density, renal function, and reproductive health in animal models provides researchers with unprecedented opportunities to study the causal relationships between cellular senescence and aging phenotypes

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It is intended to be administered by subcutaneous, intramuscular, or intravenous injection