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A Narrative Review of BPC-157 for Musculoskeletal Healing Evaluated BPC-157's molecular mechanisms and therapeutic potential for musculoskeletal injuries including tendons, ligaments, and cartilage, noting promising preclinical results and discussing the safety profile relevant to clinical translation (Curr Rev Musculoskelet Med, 2025)

This is the central regulatory problem that full FDA approval would need to solve and it is the reason PCAC reviews for peptides like BPC-157 often hinge on available safety data rather than efficacy evidence from controlled human studies

Some complications improve with appropriate treatment, but others, such as problems with the nervous system, can be permanent

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