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Mechanistically, these neuroprotective effects are underpinned by the activation of canonical GLP-1 R signaling pathways within the retina

Gut microbiota-related bile acid metabolism-FXR/TGR5 axis impacts the response to anti-47-integrin therapy in humanized mice with colitis

2.4 Ethical considerations The study was accepted for Voluntary Harmonization Procedure (VHP673, VHP2015061) and approved by ethics committees and regulatory authorities in Sweden and Austria (EudraCT No: 2015-001628-45