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Oxidative stress was also assessed through markers such as nitrotyrosine and 4-hydroxynonenal

The combination of probiotics and oxytocin produced greater improvements in social responsiveness, aberrant behaviors, and clinician-rated global functioning than either treatment alone, and was associated with favorable shift in gut microbiome network structure

Patients with high cardiovascular risk may benefit most from weight loss interventions, but they also require optimisation of all modifiable risk factors, including cholesterol management with statins where indicated