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Women receiving [weight-loss jabs] would likely have entered pregnancy at a lower weight than they otherwise would have, and this weight difference is extremely difficult to fully account for in observational analyses, he said

Its strong copper coordination is thought to improve its pharmacokinetic profile by allowing slow, localized action rather than broad systemic exposure

This was especially true in a sub-group of 15 patients who were actively deteriorating on conventional therapy (within this subgroup, conventional therapy caused a weight gain of 0.25 kg/day, whereas hyperdiuresis resulted in a loss of 1.2 kg/day