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Research showed the extracellular striatal level of the serotonin metabolite 5-HIAA rose to approximately 180% within 14 hours of Semax administration in rodents, pointing to enhanced serotonergic activity

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Furthermore, no prior knowledge of drugs or diseases is required, making the profile-based approach widely applicable

Additionally, estrogen-dependent signaling pathways are involved in regulating the balance between proliferation and differentiation of neural stem/progenitor cells (NSPCs), thus influencing neurogenic processes