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Total scale weight change typically ranges from 25-40 pounds with simultaneous muscle gain partially offsetting fat loss

This is in keeping with previous observations that overall GH secretion is reduced but pulse frequency unchanged in states of obesity or visceral adiposity (14,31) and likewise that fasting or weight loss increases GH secretion without altering pulse frequency (32,33)

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95% CI, 1.18 to 1.77), absent for liraglutide, especially in patients concurrently using antidepressants (ROR, 4.45