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Notably, our study of over 6000 Irish non-pregnant adults found that a deficient riboflavin status exacerbated the genetic risk of hypertension throughout adulthood, with a three-fold excess risk when the TT genotype occurred in combination with deficient riboflavin status compared to those without this polymorphism and normal riboflavin status (Reference Ward, Hughes and Strain111)

However, insurance plans typically do not cover drugs for their off-label uses, so the coverage request will likely be denied

Methylene blue in particular only affects MAO-A