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Through downregulating monocyte chemoattractant protein-1 expression, semaglutide treatment, an FDA-approved GLP-1 RA medicine targeting Type II diabetes mellitus (T2DM) (Christou et al., 2019), inhibited monocyte migration and infiltration from the circulatory system to inflammatory regions (Pontes-da-Silva et al., 2022)

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Lower Risk of Growth-Related Side Effects: Because it does not appear to raise IGF-1 significantly, the peptide may carry fewer systemic risks than traditional growth hormone therapies