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Last reviewed: July 17, 2026 Last updated: July 17, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

The pivotal clinical trials for Wegovy, including the STEP programme (Semaglutide Treatment Effect in People with obesity), involved thousands of participants followed for up to 68 weeks

The medication is contraindicated for patients with seizure disorders, chronic opioid users, and uncontrolled hypertension

Akkermansia helps support gut lining health and indirectly supports GLP-1 Production