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1 Center for Clinical Metabolic Research, Gentofte Hospital, Hellerup, Denmark, 2 Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, 3 Zealand Pharma A/S, Sborg, Denmark, 4 Section of Biostatistics, Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, 5 Gentofte Hospital, Hellerup, Denmark, 6 Steno Diabetes Center Copenhagen, Herlev, Denmark, 7 Novo Nordisk, Sborg, Denmark