Mucosal Immunol 13(4):637651 Wong CK, McLean BA, Baggio LL, Koehler JA, Hammoud R, Rittig N et al (2024) Central glucagon-like peptide 1 receptor activation inhibits Toll-like receptor agonist-induced inflammation
This upregulates genes involved in fatty-acid uptake/oxidation, OXPHOS, the TCA cycle, and mitochondrial biogenesis, shifting substrate use toward lipids and increasing energy expenditure
Luckily, there are a few effective treatment options, such as B12 injections vs oral therapy
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