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"High school is hard, and being a girl is hard," Sophia said, adding of the impact of losing weight, "Just feeling better in my own body has made a big difference. "Something I've done since middle school is compare myself to all the other girls that I see and wondering, why can't I be like that," Francesca said, adding of the data showing more girls than boys are on GLP-1 drugs, "I'm not very surprised." Mangarelli, who works at Lurie Childrens Hospital, where Francesca was treated, said she tries to strike a balance in her practice between body acceptance with young female patients and the reality that weight loss can improve a child's health both in the short and long term