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Lipid panel improvements (lower triglycerides, improved HDL/LDL ratio) typically appear within the first 3 to 6 months of treatment

Song M, Schuschke DA, Zhou Z, Chen T, Pierce WM Jr, Wang R, et al

The currently approved information collection burden estimate for this measure assumes an average of 289 cases are reported annually per HOPD, and HOPDs require approximately 2.9 minutes (0.049 hours) per case to perform the necessary chart abstraction and report measure data

The effect of kidney disease, in particular, is quite pronounced: pre-dialysis patients may have twice the level of TMAO, and hemodialysis patients may have 10 times the level of TMAO as otherwise healthy patients