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As investigated in several in vitro , in vivo and in clinical studies, Pycnogenol French maritime pine bark extract showed antioxidative effects, anti-inflammatory abilities, beneficial effects on endothelial function and reinforcing effects on the extracellular matrix

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In addition to natural aging, environmental causes include: Chronic exposure to chemical toxins Cadmium exposure Alcohol use Smoking Pollution Poor diet (Standard American Diet (SAD)) Stress Certain medications (Tylenol) UV radiation exposure Certain illnesses are known to decrease glutathione levels

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