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AKT seems to play a central role as its phosphorylation appears to be severely affected in several models of both type 1 diabetes mellitus (T1DM

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Dis Mod Mec 5(2):259269

The great improvement detected in ED degree category should be regarded with caution considering that, in the l-ARG cohort, only 24% of patients, mainly belonging to the baseline category of mild ED, reached IIEF-6 scores compatible with absence of ED, whereas the majority of patients improved the category by remaining within the range of ED