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However, United Healthcare, Blue Cross Blue Shield, Cigna, Medicare, and Medicaid may offer insurance for tirzepatide treatment, necessitating prior authorization

Authors Note: The authors recognize the fast-evolving nature of GLP-1 research and trends and will endeavour to ensure the article remains current with emerging GLP-1 RA data.

Major trials did not identify anxiety as a primary safety concern, but real-world reports and neurobiological mechanisms suggest susceptible individuals may experience mood shifts during treatment initiation

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