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IEEE Transbiomed Eng

Oral dissolving strips: Strip formats can be discussed as a formulation approach involving film design, dissolution behavior, packaging stability, and research-use handling

For in vivo models, sub-threshold doses can be applied over many days as cumulative, chronic doses, whereas ex vivo models are subject to tissue degradation, and therefore often use acute, super-threshold doses

These include: Nausea, vomiting, and diarrhoea (very common, especially during dose escalation) Reduced appetite and abdominal discomfort Constipation Risk of hypoglycaemia when used with insulin or sulphonylureas Pancreatitis and gallbladder disease have been reported Thyroid C-cell tumours have been observed in animal studies, though the relevance to humans is unknown Important safety considerations when using both treatments include: Mounjaro can reduce the effectiveness of oral contraceptives due to delayed gastric emptying