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Of those, 122,680 cases will be in situ (noninvasive), confined to the top layer of skin (the epidermis), and 112,000 cases will be invasive, penetrating the epidermis into the skins second layer (the dermis)

The animals were provided with 1.3 bis( p -Hydroxyphenyl)urea compound at 12.5, 25, 50, 100, and 200 mg/Kg BW

Research Diets, D12108 C, 1.25% cholesterol) or an ALC-supplemented diet (300 mg/kg, Changzhou Shuiyushuer Company, Changzhou, China) for 4 weeks ( n = 6 mice per group)