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Specific intervention scenarios of GLP-1 on cellular energy economics Treatment of diabetes: correcting the "imbalance of energy distribution" The core pathology of type 2 diabetes is insulin resistance and beta cell function failure, which leads to the imbalance of energy distribution: the intake of glucose by muscle and adipose tissue is reduced, the liver gluconeogenesis is increased, and the levels of glucose and FFA in the blood are increased, forming a vicious cycle of "hyperglycemia hyperlipidemia"

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Similar content being viewed by others Introduction The currently recommended pharmacological treatment approach for individuals with type 2 diabetes (T2D) includes oral non-insulin glucose-lowering medications, injectable glucagon-like peptide 1 receptor agonists (GLP-1RAs), and insulin as the disease progresses [1,2,3]

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