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Research goals: Longevity & Anti-Aging, Metabolic & Weight Description 5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule, membrane-permeable inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme that converts nicotinamide and S-adenosyl-l-methionine (SAM) into 1-methylnicotinamide and S-adenosyl-l-homocysteine

The medication Ozempic (generic name: semaglutide) has been trending over the past year or so, and has mostly been popularized by celebrities for its weight loss effects

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Patients: A total of 397 adult patients with T2D inadequately controlled on basal insulin with or without metformin were randomized to once-weekly Ozempic injection 0.5 mg (n=132), Ozempic injection 1 mg (n=131), or placebo (n=133)