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These defense mechanisms protect the RBCs not only from ROS generated as a byproduct of released oxygen from hemoglobin but also from ROS generated by NADPH oxidase and, in reticulocytes, from mitochondria-derived ROS during oxidative phosphorylation

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Meanwhile, acetaminophen toxicity is the leading cause of both acute liver injury and acute liver failure in this country

Diclofenac and eugenol hybrid with enhanced anti-inflammatory activity through activating HO-1 and inhibiting NF-B pathway in vitro and in vivo