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The proper designation for this class of drugs is sulfonamide but they became knows as sulfa antibiotics with their widespread use as powders and pills during WW ll

Substituting a helix-favouring alanine at that position is a potency modification of a kind long documented in the GRF structureactivity literature it raises GH-releasing potency in isolated pituitary cells, an assay that reflects receptor affinity rather than pharmacokinetics

If not, consider adjusting volume, intensity, or programming

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